A Breakthrough Therapyin WHIM Syndrome
A Therapy That Targets the Underlying Cause of WHIM Syndrome to
Help Improve Immune Function
XOLREMDI is an oral prescription medicine used in people 12 years of age and older with WHIM (warts, hypogammaglobulinemia, infections and myelokathexis) syndrome to increase the number of certain white blood cells (neutrophils and lymphocytes) circulating in the bloodstream.
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IMPORTANT SAFETY INFORMATION
What should I tell my healthcare provider before taking XOLREMDI?
Before taking XOLREMDI, tell your healthcare provider if you are pregnant, nursing, or plan to become pregnant. XOLREMDI can harm your unborn baby. You must use a reliable method of birth control (contraception) during treatment and for three weeks after you stop taking XOLREMDI. Talk to your healthcare provider about options for effective birth control and the best way to feed your baby while taking XOLREMDI.
Tell your healthcare provider if you have kidney, liver, or heart problems.
Tell your healthcare provider about all the prescription and over-the-counter medicines you take, as well as vitamins and herbal supplements, such as goldenseal and St. John's Wort. XOLREMDI may affect the way other medicines work, and other medicines may affect how XOLREMDI works. It is especially important to tell your healthcare provider if you are taking a type of pain medicine called opioids or any medications for depression or other mental health disorders, abnormal heart rhythm, high blood pressure, or breast cancer. If you are taking these medications while you are taking XOLREMDI, your healthcare provider may stop XOLREMDI, decide to change your dose, or monitor you more closely.
You should not eat grapefruit or drink grapefruit juice while taking XOLREMDI.
What are the possible side effects of XOLREMDI?
In patients with certain risk factors, XOLREMDI may cause a serious heart rhythm problem (QT prolongation).
The most common side effects of XOLREMDI are low platelet count (thrombocytopenia), rash (including a kind of rash called pityriasis), nasal irritation, nosebleeds, vomiting, and dizziness.
These are not all the possible side effects of XOLREMDI. Tell your healthcare provider if you have any side effects that bother you or do not go away. For more information, ask your healthcare provider. You are encouraged to report side effects of prescription drugs to the FDA at www.fda.gov/medwatch or by calling 1-800-FDA-1088. You may also call X4 Pharmaceuticals at 1-866-MED-X4MI (1-866-633-9464).
WHAT IS XOLREMDITM (mavorixafor)?
XOLREMDI is an oral prescription medicine used in people 12 years of age and older with WHIM (warts, hypogammaglobulinemia, infections and myelokathexis) syndrome to increase the number of certain white blood cells (neutrophils and lymphocytes) circulating in the bloodstream.
Please see the full Prescribing Information for XOLREMDI.